Richard D Carvajal, MD

Hematology

Richard D Carvajal, MD

Hematology

Specialties: Hematology, Medical Oncology, Cancer CareMore specialties
Accepting new patients
Accepts Virtual Visits

Location Info


161 Fort Washington Avenue
Floor 9
New York, NY 10032
US

Hours


Store Hours:

Day of the WeekHours
Mon9:00 AM - 5:00 PM
Tue9:00 AM - 5:00 PM
Wed9:00 AM - 5:00 PM
Thu9:00 AM - 5:00 PM
Fri9:00 AM - 5:00 PM
SatClosed
SunClosed

Insurances Accepted


Please contact the doctor's office directly to verify that your particular insurance is accepted.

    HMO
    PPO
    POS
    Student Health
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    Aetna Signature Administrators
    NY Signature
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    Essential Plan
    Medicaid Managed Care
    Special Needs
    Medicare Managed Care
    Special Needs
    PPO
    HMO
    POS
    EPO
    Great West (National)
    PPO
    Medicare Managed Care
    HMO
    POS
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    EPO
    ConnectiCare
    Select Care (Exchange)
    Essential Plan
    Medicare Managed Care
    Medicaid Managed Care
    Vytra
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    Child/Family Health Plus
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    PPO
    EPO
    Medicare Managed Care
    HMO
    Child/Family Health Plus
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    Essential Plan
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    Leaf (Exchange)
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    Traditional Medicare
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    Essential Plan
    HMO
    Medicaid Managed Care
    Freedom
    Liberty
    HMO
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    HMO
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    Columbia University Employee Plan
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    Empire Plan
    SelectHealth
    Medicare Managed Care
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    HMO
    PPO
    POS
    Student Health
    EPO
    Aetna Signature Administrators
    NY Signature
    NYP Employee Plan
    Medicare Managed Care
    Essential Plan
    Medicaid Managed Care
    Special Needs
    Medicare Managed Care
    Special Needs
    PPO
    HMO
    POS
    EPO
    Great West (National)
    PPO
    Medicare Managed Care
    HMO
    POS
    PPO
    EPO
    ConnectiCare
    Select Care (Exchange)
    Essential Plan
    Medicare Managed Care
    Medicaid Managed Care
    Vytra
    Essential Plan
    Child/Family Health Plus
    Medicaid Managed Care
    PPO
    EPO
    Medicare Managed Care
    HMO
    Child/Family Health Plus
    Medicaid Managed Care
    Medicare Managed Care
    Essential Plan
    Child/Family Health Plus
    Medicaid Managed Care
    Medicare Managed Care
    Leaf (Exchange)
    Local 1199
    MagnaCare
    Traditional Medicare
    Railroad
    Multiplan
    Child/Family Health Plus
    Essential Plan
    HMO
    Medicaid Managed Care
    Freedom
    Liberty
    HMO
    Special Needs
    HMO
    POS
    PPO
    Columbia University Employee Plan
    Compass (Exchange)
    Medicaid (Community Plan)
    Medicare Managed Care
    Empire Plan
    SelectHealth
    Medicare Managed Care
    Special Needs
    Medicare Managed Care
    Medicaid Managed Care

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About Richard D Carvajal, MD


As the Director of Experimental Therapeutics and Director of the Melanoma Service at Columbia University Medical Center, Dr. Carvajal is focused on the development of novel therapies for patients with melanoma and other cancers, with the overall objective of controlling and curing these diseases.


To achieve this goal, he has used the increasing knowledge of the underlying biology of cancer to rapidly integrate this knowledge, novel therapeutic agents, and efficient trial design in order to improve the outcomes of cancer patients everywhere. Working closely with the laboratory scientists, the group is using the techniques of molecular biology to identify specific proteins, genes, or other molecules that influence the growth of each person's cancer, with the goal of selecting the most promising therapies for individual patients.


Dr. Carvajal's melanoma research has included the study and treatment of uncommon clinical and molecular subsets of melanoma such as melanomas arising from the eye (uveal melanomas), from the mucosal surfaces of the body (mucosal melanomas), and from the palms of the hands, soles of the feet, or under the fingernails (acral melanomas). Although these tumors arise from pigment cells of the body just as do the more common melanomas that arise from the skin (cutaneous melanomas), they are clinically and biologically distinct from cutaneous disease. Once metastatic (that is, spread from where it originally began to other sites in the body), these diseases have proven to be difficult to treat.


In an advance that helped to launch a new era of personalized medicine in melanoma therapy, Dr. Carvajal has led a clinical trial of imatinib (Gleevec) in patients with melanoma characterized by the presence of a mutation in a gene called KIT. While this mutation is rare in cutaneous melanoma, it is found in about 20% of mucosal and acral melanomas. Based in part on the positive results of this trial, where long-lasting tumor responses were observed in patients with these diseases, the use of imatinib in melanomas harboring KIT mutations was added to the National Comprehensive Cancer Network guidelines for the treatment of melanoma. Uveal melanoma is characterized by mutations in genes called GNAQ and GNA11 that lead to activation of a growth pathway called the MAPK pathway. Before 2013, there were no effective treatments for metastatic disease; however, another trial that Dr. Carvajal has developed and conducted identified selumetinib, a medicine that blocks the MAPK pathway, as the first effective treatment for patients with advanced uveal melanoma.


Dr. Carvajal's research has been supported by the National Cancer Institute, the Food and Drug Administration, the Conquer Cancer Foundation, the Melanoma Research Alliance, the Melanoma Research Foundation, the Empire Clinical Research Investigator Program, and the generous philanthropic support of our patients and their families. He has authored or co- authored more than 150 peer-reviewed manuscripts, books, and book chapters. He has received several awards in recognition of his work, including the Louise and Allston Boyer Young Investigator Award and the Melanoma Research Foundations CURE OM Vision of Hope Award.


In addition to Dr. Carvajal's work at Columbia University Irving Medical Center, he serves as the co-chair of the International Rare Cancer Initiative Uveal Melanoma working group, a joint initiative between the National Cancer Institute, the European Organization for Research and Treatment of Cancer, and the Cancer Research UK to enhance international collaboration in the conduct of clinical trials for uveal melanoma.


Board Certifications

  • Hematology
  • Medical Oncology

Expertise

  • Immunotherapy
  • Melanoma

Education

  • Residency: University of Michigan Hospital & Health Centers

Titles & Positions

  • Assistant Professor of Medicine at CUMC
  • Co-Leader, Precision Oncology and Systems Biology Program
  • Director, Experimental Therapeutics
  • Director, Melanoma Service

Hospital Affiliations

  • NewYork-Presbyterian / Columbia University Irving Medical Center
  • NewYork-Presbyterian Lawrence Hospital

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