As an Assistant Professor of Medicine within the Division of Hematology/Oncology at Columbia University Irving Medical Center (CUIMC), Dr. McGuinness specializes in the care of patients with breast cancer or who are at high risk of developing breast cancer. She is currently involved in patient care, clinical research, and education. Her research interests include the evaluation of novel imaging-based tools to refine breast cancer risk prediction and to predict which patients receive benefit from breast cancer therapies. As part of this work, she collaborates closely with computer scientists, data scientists, and breast radiologists at Columbia. She also serves as the principal investigator for multiple clinical trials at CUIMC that evaluate novel treatments for patients with breast cancer. She is actively involved in the SWOG Cancer Research Network, and serves as a member of the SWOG Prevention and Epidemiology and Breast Committees, as well as the SWOG Breast Translational Medicine Working Group.

Dr. McGuinness received her bachelor of arts in Biology magna cum laude from Williams College, and her medical degree with Honor from Baylor College of Medicine, where she was elected to the Gold Humanism Honor Society. She completed both her Internal Medicine residency and Hematology/Oncology fellowship at Columbia University Irving Medical Center, during which she also served as Chief Fellow and completed a Postdoctoral Research Fellowship in Biomedical Informatics. Dr. McGuinness is the recipient of multiple career development awards from the Conquer Cancer Foundation/American Society of Clinical Oncology and the Susan G. Komen Foundation, as well as a TRANSFORM KL2 Mentored Career Development Award.