Isaac George, MD
Locations and Appointments
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About Isaac George, MD
Dr. Isaac George, MD joined NewYork Presbyterian/Columbia University Medical Center in the Department of Surgery in July of 2001 as a resident in general surgery following his graduation from Duke University School of Medicine. Prior to receiving his MD, Dr. George completed a B.S. in Mechanical Engineering at Massachusetts Institute of Technology in 1997. Dr. George also completed a fellowship program in cardiothoracic surgery in 2011 as well as a fellowship program in interventional cardiology in 2012. In July, 2012 Dr. George became an Assistant Professor of Surgery and later an Associate Professor of Surgery and Medicine in 2019.
Dr. George is board certified in thoracic (cardiac) surgery. He performs all types of open and reoperative adult cardiac surgery (aortic, mitral and tricuspid valve surgery, aortic aneurysm surgery, coronary bypass grafting, robotic surgery) with a particular interest in complex valvular and aortic disease. He specializes in minimally invasive mitral valve surgery with small incisions and repair of the mitral valve. He annually performs 150-200+ open heart surgeries a year and is the busiest heart surgeon by procedure volume in New York State. He is one of the few physicians in the world trained in both cardiac surgery and interventional cardiology. Dr. George is currently the Surgical Director of the Structural Heart and Valve Center at Columbia University Medical Center. His surgical outcomes remain some of the best in the state despite taking on the highest risk cases (surgical mortality rate per year ~1.5%).
Dr. George is focused on integrating new technology and innovation into his clinical practice. He is one of the few physicians in the world trained in both cardiac surgery and interventional cardiology. He is an expert in the most current and cutting-edge procedures including Transcatheter Aortic Valve Replacement (TAVR), transcatheter valvular mitral valve repair (Mitraclip), transcatheter mitral and tricuspid valve replacement, percutaneous coronary stenting, and aortic stent grafting. He performs almost 800 transcatheter valve procedures a year, in addition to his busy open surgical practice and has personally done almost 7000 TAVR procedures. Because he is trained in multiple disciplines, he is able to combine strategies to create a treatment plan for each individual patient that is both unbiased and personalized. As Primary Investigator of national TAVR, surgical valve, and tricuspid trials, and with involvement in numerous other clinical trials, he has extensive clinical research trial experience.
There are numerous new transcatheter trials for aortic stenosis, aortic insufficiency, bicuspid aortic valves, mitral regurgitation, tricuspid regurgitation, and heart failure that Dr. George is involved. Click here for a full list and description of ongoing trials.
Dr. George is involved in both benchtop and clinical research as well. As former director of the cardiac surgery research laboratory, he oversees surgical fellows, post-doctoral students, masters students, and research assistants in both scientific projects and clinical outcomes in cardiac surgery and TAVR. His projects reflect the translational nature of the lab as well as his clinical interests. His clinical practice allows him to be uniquely positioned to advance this research with a clinical endpoint and potential therapeutic intervention as the goal.
Dr. George can be contacted directly at firstname.lastname@example.org
Watch: Meet Cardiothoracic Surgeon, Dr. Isaac George
Watch: Dr. Isaac George Discusses Advancements in Heart Valve Surgery
Watch: Decision Making in Aortic Valve Disease with Dr. Isaac George
Watch: Dr. George Discusses Stroke Risk and TAVR
Read: Dr. George Talks Hybrid Cardiac Surgery: A Viable Strategy for Select Patients
Read: What To Expect After A Coronary Artery Bypass, According To Dr. George
Read: Dr. George Participates in World's First Use of Medical Device to Protect From Stroke During TAVR
Dr. George hosts Taking it to Heart, the Columbia Heart Valve team's podcast. In each episode, Dr. George and the Columbia Heart Valve team discuss a new topic related to valvuar disease. Subscribe to Taking It to Heart.
Click here for a full list and description of ongoing trials from Dr. George.
Click here for a complete list of publications from Dr. George.
Click here to read patient reviews of Dr. George.
Watch: Recovery from COVID
Disclosures: Dr. George is a medical consultant for Atricure, MitreMedical, cardioMech, VDyne, Valcare Medical, Durvena.
- Cardiothoracic Surgery
Specialties & Expertise
- Aortic and Mitral Valve Surgery
- Aortic Aneurysm
- Aortic Aneurysm Repair
- Aortic Aneurysm Surgery
- Aortic Aneurysm With Dissection
- Aortic Arch Surgery
- Aortic Disease
- Aortic Dissection
- Aortic Stenosis
- Aortic Stent Grafts
- Aortic Surgery
- Aortic Valve Surgery
- Atrial Fibrillation, Surgical Treatment
- Bloodless Surgery
- Coronary Artery and Valvular Disease
- Coronary Artery Bypass Surgery (Off Pump)
- Heart Disease
- Heart Disease and Women
- Heart Failure
- Heart Surgery
- Heart Transplantation
- Heart Valve Disease
- Heart Valve Repair
- Heart Valve Replacement
- Heart Valve Surgery
- High Risk Surgery of the Elderly
- Minimally Invasive Aneurysm Repair
- Minimally Invasive Heart Surgery
- Minimally Invasive Valve Repair
- Mitral Valve Reconstruction
- Mitral Valve Repair
- Mitral Valve Replacement/Repair
- Mitral Valve Surgery
- Mitral/Aortic Valve Replacement
- Off Pump Coronary Bypass Surgery
- Open Heart Surgery
- Percutaneous Valve Interventions
- Pericardial Disease
- Robotic Surgery
- TAVR (Transcatheter Aortic Valve Replacement)
- Thoracic Aneurysm Repair
- Valve Reconstruction/Repair
- Valve Replacement
- Valvular Heart Disease
- Residency: NewYork-Presbyterian Hospital/Columbia University Medical Center
- Fellowship: NewYork-Presbyterian Hospital/Columbia University Medical Center
- NewYork-Presbyterian / Columbia University Irving Medical Center
- NewYork-Presbyterian Allen Hospital
- NewYork-Presbyterian Westchester
Awards & Honors
- 1995: Pi Tau Sigma, Mechanical Engineering Honor Society
- 2004: New Era Cardiac Surgery Conference Scholarship
- 2006: Blakemore Award - Best Resident Research Award, Columbia University College of Physicians and Surgeons
- 2007: Blakemore Award - Best Resident Research Award, Columbia University College of Physicians and Surgeons
- 2008: Blakemore Prize Best Resident Research Award, Columbia University College of Physicians and Surgeons
- 2015: Columbia University Department of Surgery - Kenneth Forde Research Award
- 2016: American Association of Thoracic Surgeons Graham Surgical Investigator Award
- 2017: Columbia University Deparment of Surgery - Junior Faculty Research Grant
- 2019: American Association of Thoracic Surgeons Biology Cup Winner - Best Presentation