Charles G Drake, MD, PHD

Medical Oncology

Charles G Drake, MD, PHD

Medical Oncology

Specialties: Internal Medicine, Medical OncologyMore specialties
Accepting new patients
One of America's Top Doctors - Castle Connolly Top Doctors

Location Info


161 Fort Washington Avenue
New York, NY 10032
US

Hours


Store Hours:

Day of the WeekHours
Mon9:00 AM - 5:00 PM
Tue9:00 AM - 5:00 PM
Wed9:00 AM - 5:00 PM
Thu9:00 AM - 5:00 PM
Fri9:00 AM - 5:00 PM
SatClosed
SunClosed

Insurances Accepted


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    Capital District Physician Health Plan
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    Great West (National)
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    Special Needs
    Medicare Managed Care
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    HMO
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    POS
    Student Health
    EPO
    Aetna Signature Administrators
    NY Signature
    NYP Employee Plan
    Medicare Managed Care
    Essential Plan
    Medicaid Managed Care
    Special Needs
    Medicare Managed Care
    Special Needs
    Capital District Physician Health Plan
    PPO
    HMO
    POS
    EPO
    Great West (National)
    PPO
    Medicare Managed Care
    PPO
    EPO
    Medicare Managed Care
    Child/Family Health Plus
    Medicaid Managed Care
    Medicare Managed Care
    Child/Family Health Plus
    Medicaid Managed Care
    Medicare Managed Care
    Leaf (Exchange)
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    POS
    PPO
    EPO
    ConnectiCare
    Select Care (Exchange)
    Essential Plan
    Medicare Managed Care
    Medicaid Managed Care
    Vytra
    Essential Plan
    Child/Family Health Plus
    Medicaid Managed Care
    Local 1199
    MagnaCare
    Traditional Medicare
    Multiplan
    Child/Family Health Plus
    Essential Plan
    HMO
    Medicaid Managed Care
    Freedom
    Liberty
    HMO
    HMO
    POS
    PPO
    Columbia Employee POS
    Compass (Exchange)
    Medicaid (Community Plan)
    Medicare Managed Care
    Select Health
    Medicare Managed Care
    Special Needs
    Medicare Managed Care
    Medicaid Managed Care

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About Charles G Drake, MD, PHD


Dr. Charles G. Drake is a physician-scientist with a Ph.D. in immunology, whose work focuses on understanding and fighting advanced-stage cancers with the immune system. He is known for rapidly incorporating discoveries made in the research lab into innovative clinical trials, including anti-tumor vaccines. The Drake laboratory was the first group to show that LymphocyteActivation Gene–3 (LAG-3) is a cell surface marker for CD4 cells with regulatory function (Treg) and that blockade of LAG-3 with a monoclonal antibody could restore anti-tumor immune responses by mitigating CD8 T-cell tolerance in vivo. Further work demonstrated that LAG-3 and PD-1 were co-expressed on fun...
Dr. Charles G. Drake is a physician-scientist with a Ph.D. in immunology, whose work focuses on understanding and fighting advanced-stage cancers with the immune system. He is known for rapidly incorporating discoveries made in the research lab into innovative clinical trials, including anti-tumor vaccines. The Drake laboratory was the first group to show that LymphocyteActivation Gene–3 (LAG-3) is a cell surface marker for CD4 cells with regulatory function (Treg) and that blockade of LAG-3 with a monoclonal antibody could restore anti-tumor immune responses by mitigating CD8 T-cell tolerance in vivo. Further work demonstrated that LAG-3 and PD-1 were co-expressed on functionally exhausted CD8 T cells, suggesting that blockade of multiple immune checkpoints might be required to restore anti-tumor immunity. These discoveries were then translated into clinical trials. His most recent work has focused on the body’s immunological response to radiation therapy and how immunotherapy and radiation therapy can be used in concert to treat cancer. His research has been published in prestigious journals such as the New England Journal of Medicine, Cancer Research, the Journal of Clinical Investigation, and the Journal of Clinical Oncology. Prior to joining NewYork-Presbyterian/Columbia, Dr. Drake served as the co-director of the Cancer Immunology Program at Johns Hopkins Kimmel Cancer Center. He is also a professor of oncology, urology, and immunology. As co-director of the Prostate Cancer Multi-Disciplinary Clinic, he developed a novel transgenic model of prostate cancer, in which a unique antigen is expressed exclusively in the prostate gland and in prostate tumors. Dr. Drake received both his bachelor’s degree in electrical engineering and his master’s degree in biomedical engineering from Rutgers University. He completed a Ph.D. program at the National Jewish Center for Immunology and Respiratory Medicine at the University of Colorado Health Sciences Center, and later earned his M.D. from the University of Colorado as part of the MSTP program. He did his internship and residency in internal medicine at the Osler Medical Service of Johns Hopkins Hospital, and did his medical oncology fellowship training in the Johns Hopkins Department of Oncology.

Expertise

  • Clinical Research Trials
  • Genitourinary Cancer
  • Immunology

Education

  • Internship: Johns Hopkins Hospital
  • Residency: Johns Hopkins Hospital
  • Fellowship: Johns Hopkins Hospital

Titles & Positions

  • Co-Director, Cancer Immunotherapy Programs
  • Co-leader, Tumor Biology and Microenvironment Program.
  • Professor of Medicine

Hospital Affiliations

  • NewYork-Presbyterian / Columbia University Irving Medical Center

Awards & Honors

  • 1984 Eta Kappa Nu - Electrical Engineering Honor Society
  • 1984, 1985 Deans List, Rutgers University College of Engineering
  • 1993 Viola Vestal Coulter Foundation Scholarship for Graduate Research
  • 1993, 1994 Award For Outstanding Research; University of Colorado Student Research Forum
  • 1994 E.E. Osgood Award For Highest Ranked Abstract by a Student. Western Society for Clinical Research
  • 1996 Election to Alpha Omega Alpha (AOA) - Medical Honor Society
  • 1997 American College of Physicians Student Abstract Competition(Clinical Vignette Award)
  • 1997 Edward Stoiber Scholar Award for Outstanding Scholarship during All Four Medical School Years
  • 2001 Aventis Fellow - Johns Hopkins Department of Oncology
  • 2004 Damon Runyon - Lilly Clinical Investigator Award
  • 2006 Director's Teaching Award in Clinical Science; Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
  • 2006 V Foundation - Scholar Award
  • 2010 Prostate Cancer Foundation - Creativity Award
  • 2011 Society for Immunotherapy for Cancer- Volunteer Recognition Award
  • 2013 Director's Teaching Award in Laboratory-Based Cancer Research; Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
  • 2015 Resident's Teaching Award, The Brady Urological Institute at Johns Hopkins

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