Dr. Del Portillo is a surgical pathologist specializing in gastrointestinal, pancreas, and liver pathology, with a special interest in pre-cancerous and cancerous lesions of the GI tract. His practice includes routine and complex biopsies and resection specimens from adult and pediatric populations; transplantation specimens from GI, pancreas, and liver; and a consultation service. Dr. Del Portillo regularly attends multidisciplinary conferences including Barrett's esophagus conference and gastric and colorectal tumor boards.

Dr. Del Portillo is actively involved in training and education of medical students, residents, and fellows, and earned the Dr. Karl Perzin Award for Excellence in Anatomic Pathology Teaching. He serves as the director of the GI/pancreas/liver pathology fellowship program.

Dr. Del Portillo earned his MD and PhD from Icahn School of Medicine, trained at New York Presbyterian-Columbia University Irving Medical Center for Anatomic Pathology, and completed his GI/pancreas/liver pathology fellowship at Columbia University. He has been an Assistant Professor at Columbia since 2016.