Antonia R Sepulveda, MD

Pathology - Anatomic

Antonia R Sepulveda, MD

Pathology - Anatomic

Specialties: Pathology - AnatomicMore specialties

Location Info

622 West 168th Street
New York, NY 10032

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About Antonia R Sepulveda, MD

Antonia R. Sepulveda MD, PhD is Professor and Vice Chair for Translational Research and Director of the Division of Gastrointestinal Pathology at Columbia University Medical Center. She is an expert in gastrointestinal pathology and molecular diagnostic pathology of cancer. Her clinical practice provides specialized gastrointestinal, biliary and pancreas pathology diagnostic services with integration of molecular testing utilizing genomics, epigenomics and specific tumor biomarkers for personalized cancer management and precision medicine of digestive organ cancers and pre-cancer conditions (esophageal cancer and Barrett's esophagus, gastric, colorectal, pancreas and biliary cancers and pre-cancer risk lesions). Dr. Sepulveda leadership is nationally recognized. She has been the lead co-chair for the Molecular testing guidelines for colorectal cancer, a combined initiative of the American Society for Clinical Pathology, College of American Pathologists Pathology and Laboratory Quality Center, Association for Molecular Pathology and the American Society of Clinical Oncology.

Dr. Sepulveda research is focused on an innovative integromics cancer research program exploring computationally generated networks integrating the molecular mechanisms and biomarkers of gastric and esophageal and pancreatic cancers and pre-cancer lesions. Through these cutting edge approaches Dr. Sepulveda hopes to define novel tumor types and regulatory pathways of cancer development and progression, and biomarkers for their diagnosis and therapy. Dr. Sepulveda has over 120 publications (original research, reviews, chapters and books).


Board Certifications

  • Pathology - Anatomic


  • Barrett's Esophagus
  • Bile Duct Cancer
  • Cancer of Gallbladder and Bile Ducts
  • Colon Cancer and Polyps
  • Colon Disorder
  • Colon Tumors
  • Colorectal Cancer
  • Disease of Colon
  • Esophageal Cancer
  • Esophageal Disorders
  • Family History of Colorectal Cancer
  • Family History of Gastric Cancer
  • Gastric Cancer
  • Gastric Neoplasms
  • Gastrointestinal Cancer
  • Gastrointestinal Disorders In Oncology
  • Gastrointestinal Malignancies
  • Gastrointestinal Pathology
  • Gastrointestinal Tumors
  • Molecular Biology
  • Molecular Cancer Testing
  • Molecular Diagnostics
  • Molecular Pathology
  • Pancreas Cancer
  • Pancreatic Cancer
  • Pancreatic Tumor
  • Pathology


  • Residency: Baylor College of Medicine Affiliated Hospitals Texas
  • Fellowship: Baylor College of Medicine Affiliated Hospitals Texas
  • Medical School: Universidade De Lisboa
  • Internship: Hospital Civis Of Lisbon

Titles & Positions

  • Director, Division of Gastrointestinal Pathology
  • Professor of Pathology & Cell Biology at CUMC
  • Vice Chair for Translational Research

Hospital Affiliations

  • NewYork-Presbyterian / Columbia University Irving Medical Center

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